Acyl Halides
Medchemexpress LLC N4-Benzoyl-2 -O-meth 250mg
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Medchemexpress LLC N-Benzoyl-(2R,3S)-3-phenylisoserine | 132201-33-3 | 50 MG
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain, crucial for the strong antitumor activity of Taxol. It has a molecular weight of 285.29, a chemical formula of C16H15NO4, and appears as a white to off-white solid with 99.48% purity.
- Crucial for the strong antitumor activity of Taxol
- Exhibits cellular effects, showing 62% inhibition in B16 melanoma cells at 42 μM
- Has an IC50 of > 100 μM in rat L6 cells after 70 hours
- White to off-white solid appearance
- Purity of 99.48%
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 25 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, particularly against indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Roslin 2 bromide | 29574-21-8 | 99.0% | C13H19BrN4 | 1 MG
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that exhibits anticancer effects. It functions by binding to FAK, thereby disrupting the interaction between FAK and p53.
- Decreases cancer cell viability and clonogenicity in a p53-dependent manner.
- Increases p53 transcriptional activity, which is inhibited by FAK, using p21, Mdm-2, and Bax-promoter targets.
- Leads to increased expression of p53 targets: p21, Mdm-2, and Bax proteins.
- Significantly reduces tumor growth, disrupts the FAK and p53 complex, and up-regulates p21 in HCT116 p53+/+ xenografts (not in HCT116 p53-/- xenografts).
Medchemexpress LLC Oleyl bromide | 6110-53-8 | 98.36% | 331.37 | 50 MG
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound capable of undergoing a ring-opening reaction through a process known as "encapsulation." It can also serve as a starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound.
- Can carry out ring-opening reactions via "encapsulation."
- Used as a starting material in the synthesis of oleylphosphonates.
- Ships at room temperature in continental US.
- Pure form storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
Apexbio Technology LLC Methylbenactyzine-Bromide
Methylbenactyzine Bromide (CAS No 3166-62-9) is a synthetic anticholinergic agent primarily used in neuromuscular research Originating from studies on muscarinic receptor antagonists this compound targets muscarinic acetylcholine receptors inhibiting neurotransmission in cholinergic pathways Its efficacy is noted within the nanomolar to low micromolar range in in vitro assays making it a valuable tool in pharmacological studies focused on modulating neuronal activity The compound is commonly applied in cell models to explore neurophysiological processes and in animal studies to assess its impact on muscle relaxation and potential therapeutic effects for conditions like muscle spasms Additionally it serves as a reference compound in drug screening programs aimed at identifying new anticholinergic agents Experimental concentrations typically depend on the specific research design allowing for tailored applications across varied experimental settings
Apexbio Technology LLC Methylbenactyzine-Bromide
Methylbenactyzine Bromide (CAS No 3166-62-9) is a synthetic anticholinergic agent primarily used in neuromuscular research Originating from studies on muscarinic receptor antagonists this compound targets muscarinic acetylcholine receptors inhibiting neurotransmission in cholinergic pathways Its efficacy is noted within the nanomolar to low micromolar range in in vitro assays making it a valuable tool in pharmacological studies focused on modulating neuronal activity The compound is commonly applied in cell models to explore neurophysiological processes and in animal studies to assess its impact on muscle relaxation and potential therapeutic effects for conditions like muscle spasms Additionally it serves as a reference compound in drug screening programs aimed at identifying new anticholinergic agents Experimental concentrations typically depend on the specific research design allowing for tailored applications across varied experimental settings